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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
2.73
Human Site:
S554
Identified Species:
5
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S554
I
S
G
G
S
S
S
S
S
K
S
G
M
C
L
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
P521
E
G
C
L
T
M
V
P
S
E
K
E
V
E
P
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
P320
I
V
Y
R
D
L
K
P
E
N
V
L
L
D
N
Dog
Lupus familis
XP_542675
460
51324
S452
V
E
E
A
A
P
A
S
K
S
G
M
C
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
P554
I
T
T
E
E
A
A
P
T
A
K
S
G
M
C
Rat
Rattus norvegicus
Q63651
564
63750
P554
I
T
V
E
E
A
A
P
T
A
K
S
G
M
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
A554
G
P
G
E
D
E
T
A
S
S
S
K
S
G
V
Chicken
Gallus gallus
NP_990026
593
64642
G583
N
A
E
P
G
S
G
G
G
T
R
S
A
T
C
Frog
Xenopus laevis
NP_001087513
575
66421
P547
R
G
L
P
S
P
Q
P
K
K
G
L
L
Q
C
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Y425
E
A
F
L
G
F
S
Y
A
P
A
M
D
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
K675
N
A
A
P
E
P
D
K
A
G
C
F
P
F
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
E578
P
D
G
I
N
M
D
E
R
R
N
G
T
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
N800
N
Q
E
K
N
M
N
N
S
H
S
Q
M
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
20
6.6
13.3
6.6
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
13.3
33.3
N.A.
33.3
33.3
N.A.
40
13.3
20
26.6
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
8
8
16
24
8
16
16
8
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
8
8
31
% C
% Asp:
0
8
0
0
16
0
16
0
0
0
0
0
8
16
0
% D
% Glu:
16
8
24
24
24
8
0
8
8
8
0
8
0
8
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
8
0
8
8
% F
% Gly:
8
16
24
8
16
0
8
8
8
8
16
16
16
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
31
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
8
16
16
24
8
0
0
8
% K
% Leu:
0
0
8
16
0
8
0
0
0
0
0
16
16
8
8
% L
% Met:
0
0
0
0
0
24
0
0
0
0
0
16
16
16
0
% M
% Asn:
24
0
0
0
16
0
8
8
0
8
8
0
0
0
8
% N
% Pro:
8
8
0
24
0
24
0
39
0
8
0
0
8
0
8
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
8
0
8
0
% Q
% Arg:
8
0
0
8
0
0
0
0
8
8
8
0
0
0
8
% R
% Ser:
0
8
0
0
16
16
16
16
31
16
24
24
8
16
0
% S
% Thr:
0
16
8
0
8
0
8
0
16
8
0
0
8
8
0
% T
% Val:
8
8
8
0
0
0
8
0
0
0
8
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _